CAT: | RP-H-IL7Rα-Fc |
Category: | Recombinant Proteins |
Specifications> | |
Product Name: | Recombinant Human IL-7R alpha Protein with C-terminal Fc Tag |
Background: | The interleukin-7 receptor is a protein that exists on the surface of cells. The protein is a heterodimer composed of two subunits: interleukin-7 receptor subunit alpha (IL-7RA, CD127) and common-γ chain receptor (CD132). The interleukin-7 receptor is expressed on a variety of cell types, including naive and memory T cells, among many others. The interleukin-7 receptor has been found to be crucial in lymphocyte development. T-cell acute lymphoblastic leukemia, multiple sclerosis, rheumatoid arthritis, and juvenile idiopathic arthritis are among the disorders linked to the Interleukin-7 receptor. |
Source: | Human 293 cells (HEK293) |
UniProt ID: | P16871-1 |
Sequence: | Human IL-7R alpha (Glu 21 - Asp 239) + Human IgG1 (Pro100-Lys330) (N-terminus to C-terminus) |
Purification: | Protein A/G purified and size-HPLC |
Purity: | >95% as determined by SDS-PAGE. |
Activity: | Measured by its binding ability to human IL-7 protein (0.2 µg) with an EC50=0.032 µg/ml. |
Endotoxin Level: | <0.10 EU per 1 µg of the antibody by the LAL method |
Formulation: | 0.2 µm filtered solution in PBS |
Reconstitution: | Reconstitute at 0.5 mg/ml in sterile 1xPBS |
Predicted Molecular Weight: | 52 kDa |
Shipping: | The product is provided in polar packs. Upon receiving, store it immediately at -20 to -70°C |
Storage: | Steer clear of frequent freeze-thaw cycles and use a manual defrost freezer. • 12 months from the date of receipt at -20 to -70°C, as specified. • 1 month at 2–8°C under sterile circumstances |
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